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Table 5 Effect of drugs on metabolic bone disease

From: Profile of metabolic bone disease in extremely low birth weight (ELBW) and very low birth weight (VLBW) neonates

Drugs

S. phosphorus (< 5.5 mg/dl)

S. phosphorus (> 5.5 mg/dl)

P value

S. AP (> 900 IU/dl)

S. AP (< 900 IU/dl)

P value

At 4 weeks

 Caffeine + steroid

n = 10

09 (90%)

01 (10%)

0.0001

09 (90%)

01 (10%)

0.0001

 Caffeine + diuretic

n = 3

03 (100%)

00 (0.0%)

0.014

03 (100%)

00 (0.0%)

0.014

 Caffeine only

n = 44

34 (77.2%)

10 (22.7%)

0.0001

34 (77.2%)

10 (22.7%)

0.0001

At discharge

 Caffeine + steroid

n = 10

09 (90%)

01 (10%)

0.0001

09 (90%)

01 (10%)

0.0001

 Caffeine + diuretic

n = 3

03 (100%)

00 (0.0%)

0.014

03 (100%)

00 (0.0%)

0.014

 Caffeine only

n = 44

34 (77.2%)

10 (22.7%)

0.0001

34 (77.2%)

10 (22.7%)

0.0001

  1. S. AP (> 900 IU/dl), S. alkaline phosphatase; n, number of neonates