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Egyptian Pediatric Association Gazette
Fig. 2 | Egyptian Pediatric Association Gazette

Fig. 2

From: Relationship of thymic area with clinical-epidemiological variables and values of T-lymphocyte subpopulations in peripheral blood of children with recurrent infections

Fig. 2

Cellular immunophenotypes by flow cytometry according to the thymus area in children with recurrent infections. The multiparametric analysis (relative and absolute frequencies) is based on the values of the flow cytometry of cell subpopulations CD45+ CD3+, CD45+ CD3+ CD4+, and CD45+ CD3+ CD8+ and cell subpopulations T CD4+ and T CD8+ naïve (CD45RA+ CD27+) and memory cells (central memory cells, CM, CD45RA− CD27+; effector memory cells, EM, CD45RA− CD27−; terminally differentiated effector T cells, TEMRA, CD45RA+ CD27−). Each point represents an individual with a normal thymus area (N, gray, n = 25) and thymus hypoplasia (H, purple, n = 48). The analysis of distribution comparison between groups was carried out using the U Mann-Whitney test, with a level of significance of p < 0.05. The p-value, and its significance, was *p < 0.05. No differences were found in the CD4/CD8 index on comparing the groups. Abbreviations: IQR interquartile range

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