Table 3 Relationships of miR-182-5p and miR-590-3p with clinical data in neonates with sepsis

Sex

 Male

0.56 (0.39 − 2.42)

0.606

0.44 (0.2 − 1.11)

0.699

 Female

0.55 (0.24 − 1.97)

0.38(0.11 − 1.11)

Onset

 Early

0.50(0.24 − 2.87)

0.081

0.93(0.14 − 2.20)

0.034

 Late

0.57(0.55 − 1.97)

0.33(0.08 − 0.44)

Gestational age

 Preterm

0.38 (0.24 − 1.18)

0.032

0.93 (0.14 − 1.11)

0.492

 Full term

0.57 (0.50 − 3.29)

0.33(0.11 − 0.51)

PROM

 Yes

1.18 (0.4 − 3.29)

0.142

3.07 (2.2 − 58.89)

 < 0.001

 No

0.55 (0.24 − 1.97)

0.25 (0.08 − 0.51)

Fever

 Feverish

0.5 (0.38 − 1.97)

 < 0.001

0.44(0.08 − 0.93)

 < 0.001

 Normal

1.18 (0.09 − 3.29)

1.61(0.14 − 3.07)

Convulsion

 Yes

0.04 (0.04 − 0.55)

 < 0.001

0.05 (0.05 − 0.08)

 < 0.001

 No

0.57 (0.38 − 2.87)

0.51 (0.25 − 2.2)

Respiratory distress (RD)

 None

0.57 (0.55 − 1.97)

 < 0.0.001

0.44 (0.33 − 0.51)

 < 0.001

 RD1

0.4 (0.09 − 3.29)

2.2 (0.14 − 3.07)

 RD2

0.04 (0.04 − 0.38)

0.05 (0.01 − 0.05)

 RD3

0.5 (0.5 − 1.18)

0.25 (0.25 − 58.89)

 RD4

7.67 (0.67 − 7.67)

0.11 (0.11 − 0.11)

Apnea

 Yes

2.87 (0.55 − 1.97)

0.136

0.11 (0.08 − 0.93)

0.027

 No

0.5 (0.24 − 3.86)

0.44 (0.14 − 2.2)

Bleeding

 Yes

0.4(0.38 − 1.18)

0.014

0.51(0.05–2.2)

0.076

 No

0.55(0.24 − 3.29)

0.44(0.14–1.11)

Culture

 Positive

0.4 (0.24 − 1.97)

0.030

0.51 (0.11 − 1.11)

0.698

 Negative

0.67 (0.57 − 1.18)

0.44 (0.33 − 0.44)

Organisms

 Candida (non-albicans)

0.4 (0.4 − 2.87)

 < 0.001

2.2 (0.93 − 2.2)

0.012

 Enterobacter species

3.29 (3.29–7.67)

3.07 (0.11 − 3.07)

 Klebsiella species

0.24 (0.09 − 0.5)

0.25 (0.14 − 1.11)

 Staph.aureus

1.01 (0.04 − 1.97)

0.28 (0.05 − 0.51)

Gram stain type

 Negative

0.38 (0.24 − 0.5)

0.510

0.25 (0.14 − 1.11)

0.007

 Positive

1.97 (0.04 − 1.97)

0.11 (0.05 − 0.51)

Antibiotic resistance

 AmpC beta lactamase

3.29 (0.24 − 3.29)

0.049

1.11 (0.11 − 3.07)

 < 0.001

 MDR

0.38 (0.09 − 0.5)

0.14 (0.01 − 0.25)

 MRSA

1.01 (0.04 − 1.97)

0.28 (0.05 − 0.51)