Neurological manifestation | |||||
---|---|---|---|---|---|
Variables | Absent (N = 103) | Present (N = 47) | P | ||
N. | % | N | % | ||
Sex | |||||
Male | 55 | 66.3 | 28 | 33.7 | 0.383 |
Female | 48 | 71.6 | 19 | 29.4 | |
Age | |||||
years | 59 | 100 | 0 | 0 | < 0.001 |
≥ 16 years | 44 | 48.4 | 47 | 51.6 | |
BMI (kg/m2) | |||||
Mean ± SD | 19.02 ± 2.37 | 21.99 ± 2.63 | 0.000 | ||
Duration of disease (years) | 13.91 ± 3.30 | 17.58 ± 1.78 | 0.000 | ||
Mean ± SD | |||||
Transfusion frequency | |||||
timesyear | 27 | 27.2 | 1 | 2.1 | 0.001 |
≥ 10 times/year | 76 | 73.2 | 46 | 97.9 | |
Splenomegaly | |||||
No | 17 | 40.5 | 25 | 59.5 | 0.005 |
Yes | 85 | 79.4 | 22 | 20.6 | |
Splenectomy | |||||
No | 73 | 68.9 | 33 | 31.1 | 0.928 |
Yes | 30 | 68.2 | 14 | 31.8 | |
Hepatomegaly | |||||
No | 59 | 47.6 | 65 | 52.4 | 0.005 |
Yes | 44 | 55.7 | 35 | 44.3 | |
Iron chelation therapy | |||||
Deferoxamine | 29 | 63.0 | 17 | 37.0 | 0.135 |
Deferasirox | 55 | 82.1 | 12 | 17.9 | |
Deferiprone | 16 | 72.7 | 6 | 27.3 | |
Combined | 10 | 62.5 | 6 | 37.5 |