Insights from a retrospective study: an understanding of pediatric colorectal carcinoma

Guzmán, Sofia Brenes; García, Edgar Fernando Oliver; Rojas, Edgar Guillermo Lazcano; Tinajero, Alfa Guadalupe Barraza; Meza, Daniela Hernández; Chávez, Jose Luis González; Camacho, Edgar Melo; Enríquez, Juan Carlos Nuñez

doi:10.1186/s43054-024-00246-6

Egyptian Pediatric Association Gazette

Table 1 General characteristics of the PCC patients

From: Insights from a retrospective study: an understanding of pediatric colorectal carcinoma

Subject	Early surgical intervention			Late surgical intervention
Subject	1	2	3	4	5	6
Adenocarcinoma hitologic type	signet ring cells	signet ring cells	signet ring cells	signet ring cells	signet ring cells	Well differenciated
Age (years)	17	17	16	16	16	14
Gender	M	M	F	M	M	F
Time of evolution (days)^a	15	34	15	35	15	63
Symptoms	Anemia, pain, hematochezia, signs of acute abdomen	Anemia, pain, hematochezia, signs of acute abdomen	Anemia, pain, signs of acute abdomen	Anemia, pain, hematochezia	Anemia, dolor, hematoquezia	Anemia, pain, hematochezia
Image study	CT^b	CTç Colonoscopy PET-CT	Abdominal ultrasound CTç	CTç PET-CT Panesdocopy	CTç MRCP	Abdominal ultrasound CT ç MRCP Coaxial hepatic biopsy Colonoscopy
The primary site of the tumor	Descending colon and rectosigmoid junction	Ascending colon	Descending colon	Descending colon and rectosigmoid junction	Descending colon	Rectosigmoid junction and appendix
Metástasis	Peritoneal carcinomatosis and regional lymph nodes	Regional lymph nodes, hepatic, bone, and peritoneal carcinomatosis	Distal lymph nodes, ascending colon, peritoneal carcinomatosis	Peritoneal carcinomatosis, transverse colon, regional lymph nodes, and jejunum	Peritoneal carcinomatosis and regional lymph nodes, duodenum, pancreas, spleen, and transverse colon	Regional lymph nodes, hepatic, and bone
Treatment
Early surgery^c	Laparotomy and biopsy	Laparotomy and biopsy	Laparotomy and appendectomy	No	No	No
Late surgery^d	Laparotomy for tumor obstruction and ileostomy	Laparotomy, left hemicolectomy, colostomy	No	Laparotomy for tumor obstruction and ileostomy	Laparotomy, left hemicolectomy, tumoral resection, colostomy	No
Chemotherapy	Adyuvant	Adjuvant	Neoadjuvant	Adjuvant	Ajuvant	Neoadjuvant
Inmunomoduladores	Yes	No	No	Yes	No	No
Evolution (months)^e	15	14	5	12	15	2

F female, M male
^aTime since the first symptom was detected by the patient in the initial interrogatory
^bcomputed tomography from the thorax, abdomen, and pelvis with contrast. PET CT positron emission computed tomography, MRCP magnetic resonance cholangiopancreatography
^cPatients with an initial surgery because of the presentation at admission of acute abdomen
^dPatients with no acute abdomen symptoms and did not have surgery at admission
^eTime from the first hospital admission until death

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