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Table 3 The predictive performance of lipid profile and D-dimer for PICU mortality due to sepsis

From: A prospective cohort study of severe sepsis-induced dyslipidemia and changes in D-dimer levels in children: do they affect the prognosis?

Variables

Cholesterol

(mg/dl)

Triglycerides

(mg/dl)

HDL

(mg/dl)

LDL

(mg/dl)

Apo A-V

(ng/ml)

D-dimer

(μg/mL)

Cut off point

109.2

112.5

43.3

47.4

89.5

0.87

AUC

0.62

0.49

0.55

0.54

0.56

0.85

Significance

0.1

0.9

0.5

0.5

0.4

0.001**

95% CI

(0.48–0.76)

(0.34–0.64)

(0.39–0.71)

(0.39–0.69)

(0.41–0.7)

(0.75–0.94)

Sensitivity

73.1%

70.0%

70.0%

63.3%

73.4%

93.3%

Specificity

40%

30.0%

47.0%

44.0%

32.1%

64.7%

PVP

54.9%

50.0%

56.9%

53.1%

51.9%

72.5%

PVN

59.7%

50.0%

61.1%

54.5%

54.7%

90.6%

Accuracy

56.5%

50.0%

58.5%

63.5%

52.7%

79.0%

  1. Apo A-5 Apolipoprotein A-V, AUC Area under the curve, CI Confidence interval, HDL High-density lipoprotein, LDL Low-density lipoprotein, PVN Predictive value negative, PVP Predictive value positive
  2. **Statistically highly sensitive