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Table 2 Validity and performance of specific measurements and vasoactive-inotropic score in predicting complications after cardiac surgery in pediatric patients

From: Prognostic value of combined central venous oxygen saturation and lactate in pediatric patients after cardiac surgery

Measurement

AUC

Cutoff

p-value

Sensitivity

Specificity

PPV

NPV

PLR

NLR

ScvO2 6 h after PICU admission

85.5

58.0

 < 0.001

81.6% (65.7–92.3%)

82.9% (66.4–93.4%)

83.8% (67.8–93.3%)

80.6% (64.2–92.4%)

4.75% (2.26–10.01%)

22.2% (11.2–44.1%)

Lactate level 12 h after PICU admission

75.0

1.3

 < 0.001

63.2% (46.0–78.2%)

82.0% (66.4–93.4%)

80.0% (62.0–89.3%)

67.4% (50.7–85.9%)

3.68% (1.71–7.93%)

44.5% (28.6–69.2%)

ScvO2/lactate ratio

83.0

38.3

 < 0.001

68.4% (51.3–82.5%)

80.0% (63.1–91.6%)

78.8% (61.3–89.0%)

70.0% (53.2–86.4%)

3.42% (1.7–6.9%)

0.40% (0.2–0.7%)

VIS

63.4

15.0

 < 0.001

92.1% (78.6–98.3%)

40.0% (23.9–57.9%)

62.5% (43.9–89.4%)

82.4% (59.5–90.6%)

1.54% (1.2–2.0%)

19.7% (6.2–62.9%)

MAP 18 h after PICU admission

73.6

72.0

 < 0.001

42.1% (26.3–59.2%)

97.1% (85.1%–99.9%)

94.1% (72.9–97.0%)

60.7% (43.1–98.4%)

14.74% (2.1–105.4%)

59.6% (45.2–78.6%)

  1. AUC area under the curve, PPV positive predictive value, NPV negative predictive value, PLR positive likelihood ratio, NLR negative likelihood ratio, VIS vasoactive-inotropic score, ScvO2 central venous oxygen saturation, PICU pediatric intensive care unit, MAP mean arterial pressure