Measurement | AUC | Cutoff | p-value | Sensitivity | Specificity | PPV | NPV | PLR | NLR |
---|---|---|---|---|---|---|---|---|---|
ScvO2 6 h after PICU admission | 85.5 | 58.0 | < 0.001 | 81.6% (65.7–92.3%) | 82.9% (66.4–93.4%) | 83.8% (67.8–93.3%) | 80.6% (64.2–92.4%) | 4.75% (2.26–10.01%) | 22.2% (11.2–44.1%) |
Lactate level 12 h after PICU admission | 75.0 | 1.3 | < 0.001 | 63.2% (46.0–78.2%) | 82.0% (66.4–93.4%) | 80.0% (62.0–89.3%) | 67.4% (50.7–85.9%) | 3.68% (1.71–7.93%) | 44.5% (28.6–69.2%) |
ScvO2/lactate ratio | 83.0 | 38.3 | < 0.001 | 68.4% (51.3–82.5%) | 80.0% (63.1–91.6%) | 78.8% (61.3–89.0%) | 70.0% (53.2–86.4%) | 3.42% (1.7–6.9%) | 0.40% (0.2–0.7%) |
VIS | 63.4 | 15.0 | < 0.001 | 92.1% (78.6–98.3%) | 40.0% (23.9–57.9%) | 62.5% (43.9–89.4%) | 82.4% (59.5–90.6%) | 1.54% (1.2–2.0%) | 19.7% (6.2–62.9%) |
MAP 18 h after PICU admission | 73.6 | 72.0 | < 0.001 | 42.1% (26.3–59.2%) | 97.1% (85.1%–99.9%) | 94.1% (72.9–97.0%) | 60.7% (43.1–98.4%) | 14.74% (2.1–105.4%) | 59.6% (45.2–78.6%) |