Table 2 The clinical and laboratory data of the study groups after the start of the furosemide injection
Changes after 24-h therapy (24-h data–admission data) | Changes after 48-h therapy (48 h data–admission data) | |||||
|---|---|---|---|---|---|---|
Furosemide repeated injection (n = 27) | Furosemide continuous infusion (n = 27) | P value | Furosemide repeated injection (n = 27) | Furosemide continuous infusion (n = 27) | P value | |
ΔWeight (kg) | − 0.27 ± 0.05 | − 0.33 ± 0.05 | 0.001 | − 0.49 ± 0.07 | − 0.59 ± 0.11 | 0.001 |
ΔUOP (ml/kg/h) | 2.6 ± 1.0 | 3.3 ± 1.4 | 0.037 | 1.2 ± 0.3 | 2.3 ± 1.3 | 0.001 |
ΔHR (beat/min) | − 18.5 ± 4.4 | − 23.3 ± 6.3 | 0.002 | − 27 ± 3.7 | − 28 ± 4 | 0.324 |
ΔRR (/min) | − 15.1 ± 2.6 | − 18.8 ± 2.9 | 0.001 | − 20 ± 3 | − 24.5 ± 3.3 | 0.001 |
ΔSBP (mmHg) | − 27. 8 ± 6.8 | − 26. 6 ± 9.6 | 0.613 | − 35 ± 6.5 | − 33 ± 7.7 | 0.214 |
ΔDBP (mmHg) | − 20.6 ± 5.5 | − 23.3 ± 7.6 | 0.138 | − 28 ± 5.5 | − 27.7 ± 6.9 | 0.897 |
ΔSpO2 (%) | 12.6 ± 3.4 | 12.7 ± 4.4 | 0.945 | 16.2 ± 3.8 | 16.1 ± 4.3 | 0.893 |
Δ Serum sodium (mmol/l) | 3.1 ± 1 | 2.7 ± 0.9 | 0.111 | 3.9 ± 1.6 | 4.1 ± 1.5 | 0.662 |
ΔSerum potassium (mmol/l) | − 0.31 ± 0.08 | − 0.37 ± 0.2 | 0.185 | − 0.51 ± 0.33 | − 0.56 ± 0.47 | 0.816 |
ΔSerum creatinine (mg/dl) | − 0.12 ± 0.05 | − 0.11 ± 0.06 | 0.627 | − 0.23 ± 0.06 | − 0.20 ± 0.09 | 0.248 |