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Table 1 Demographic characteristics, echocardiographic, clinical, and laboratory data of the study groups before the start of the furosemide injection

From: Furosemide continuous infusion versus repeated injection in the management of acute decompensated heart failure in infants with left to right shunt: a randomized trial

 

Furosemide repeated injection (n = 27)

Furosemide continuous infusion (n = 27)

P value

Gendera

 Male/female

16/11

15-Dec

0.414

 Ageb (month)

6.11 ± 3.18

6.06 ± 3.19

0.954

 Weightb (kg)

5.35 ± 1.52

5.24 ± 1.52

0.789

 Heightb (cm)

59.26 ± 6.77

60.70 ± 6.12

0.415

Underlying cardiac lesionsa

 VSD

6 (22.2)

9 (33.3)

0.18

 PDA

5 (18.5)

2 (7.4)

 

 VSD + ASD

9 (33.3)

12 (44.4)

 

 VSD + PDA

0

2 (7.4)

 

 ASD + PDA

5 (18.5)

2 (7.4)

 

 VSD + ASD + PDA

2 (7.4)

0

 

Echocardiography findingsa

 Left ventricular ejection fraction

47.67 ± 5.87

46.64 ± 7.32

0.578

Size of the lesions

 VSD (mm)

7.31 ± 2.09

8.19 ± 2.96

0.37

 ASD (mm)

5.44 ± 3.14

4.54 ± 2.40

0.403

 PDA (mm)

4.17 ± 1.47

5 ± 0.82

0.304

Precipitating factors of ADHFa

 Acute bronchiolitis

10 (37)

10 (37)

0.775

 Pneumonia

10 (37)

9 (33.3)

 

 Gastroenteritis

7 (25.9)

6 (22.2)

 

 Incompliance to therapy

0

2 (7.2)

 

Preadmission oral furosemide b

 Number of patients

n = 22

n = 24

 

 Dose (mg/kg/day)

1.3 ± 0.25

1.38 ± 0.34

0.374

Clinical datab

 HR (beat/min)

170.7 ± 6.2

171.6 ± 5.3

0.557

 RR (/min)

71.6 ± 5.9

73.4 ± 3.4

0.175

 SBP (mmHg)

109.2 ± 7.6

111.9 ± 6.4

0.158

 DBP (mmHg)

71.7 ± 3.7

70.1 ± 4.2

0.145

 SpO2 (%)

78.2 ± 3.6

77. 7 ± 4.4

0.692

Laboratory datab

 Serum sodium (mmol/l)

137.9 ± 2.3

138.3 ± 2.6

0.541

 Serum potassium (mmol/l)

3.67 ± 0.41

3.71 ± 0.47

0.758

 Serum creatinine (mg/dl)

0.57 ± 0.12

0.60 ± 0.12

0.432

  1. VSD Ventricular septal defect, ASD Atrial septal defect, PDA Patent ductus arteriosus, ADHF Acute decompensated heart failure, UOP Urine output, HR Heart rate, RR respiratory rate, SBP Systolic blood pressure, DBP Diastolic blood pressure, SpO2 Oxygen saturation by pulse oximetry, /min per minute
  2. Data expressed as number (percent)/ratio a or mean ± SD b and analyzed by chi-square/Fisher´s exact testa and Student’s t test b; respectively