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Table 4 Receiver Operating characteristic (ROC) curve analysis for prediction of mortality

From: ADAMTS13 in pediatric sepsis: a prognostic biomarker with potential therapeutic implications

Variable

AUCd (95% CIe)

P-value

Cutoff

Sensitivity

Specificity

ADAMTS13a, ng/ml

0.77 (0.66 – 0.89)

 < 0.001*

 ≤ 1.25

83.3%

69.6%

PIM2b, mortality %

0.72 (0.58 – 0.85)

0.003*

 ≥ 3.4

70.8%

71.7%

pSOFAc score

0.81 (0.69 – 0.92)

 < 0.001*

 ≥ 6.5

70.8%

86.7%

Platelets, 1000/µL

0.67 (0.53 – 0.80)

0.024f

 ≤ 349.5

79.2%

50%

  1. aa disintegrin-like and metalloprotease with thrombospondin type 1 motif, 13
  2. bPediatric Index of Mortality2
  3. cpediatric Sequential Organ Failure Assessment score
  4. dArea under the Receiver Operating Characteristic curve
  5. eConfidence interval
  6. *Statistically significant