From: ADAMTS13 in pediatric sepsis: a prognostic biomarker with potential therapeutic implications
Variable | Patients (n = 70) |
---|---|
General characteristics | |
Age, month | 16 (5 – 60) |
Male sex | 31 (44.3%) |
Weight, Kg | 8.4 (5.5 – 13.6) |
Category | |
Sepsis | 41 (58.6%) |
Severe sepsis | 14 (20%) |
Septic shock | 15 (21.4%) |
Complex chronic conditionl | 26 (37.1%) |
Malnutrition | 35 (50%) |
Illness severity | |
ARDSa | 9 (12.9%) |
Mechanical ventilation | 30 (42.9%) |
Ventilator-free days | 5 (2.8 – 9) |
HAIb | 18 (25.7%) |
Vasoactive medications | 21 (30%) |
Vasoactive infusion days | 0 (0 – 2) |
Vasoactive-inotropic score (day 1) | 0 (0 – 10) |
Vasoactive-inotropic score (day 2) | 0 (0 – 6.3) |
Need for renal replacement therapy | 5 (7.1%) |
MODSc (day1) | 20 (28.6%) |
MODS (day 3) | 16 (22.9%) |
PICUd stay, days | 7 (5 – 12.3) |
PIM2e mortality risk% | 2.6 (1.6 – 8.5) |
pSOFAf score (1st day) | 5 (4 – 8.5) |
Laboratory values on admission | |
CRPg, mg/dL | 24 (6 – 66) |
Hemoglobin, g/dL | 10.2 (9.4 – 11.2) |
WBCh, 1000/uL | 9.2 (4.9 – 14.1) |
ANCi, 1000/uL | 15 (8.4 – 20.9) |
Platelets, 1000/uL | 312 (158.3 – 377.5) |
Creatinine, mg/dL | 0.6 (0.4 – 0.8) |
ALTj, U/L | 24 (16 – 48.8) |
ADAMTS-13k, ng/mL | 1.30 (0.88 – 3.13) |