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Table 1 Demographic, clinical, and baseline laboratory data of patients

From: ADAMTS13 in pediatric sepsis: a prognostic biomarker with potential therapeutic implications

Variable

Patients (n = 70)

General characteristics

Age, month

16 (5 – 60)

Male sex

31 (44.3%)

Weight, Kg

8.4 (5.5 – 13.6)

Category

 Sepsis

41 (58.6%)

 Severe sepsis

14 (20%)

 Septic shock

15 (21.4%)

Complex chronic conditionl

26 (37.1%)

Malnutrition

35 (50%)

Illness severity

ARDSa

9 (12.9%)

Mechanical ventilation

30 (42.9%)

Ventilator-free days

5 (2.8 – 9)

HAIb

18 (25.7%)

Vasoactive medications

21 (30%)

Vasoactive infusion days

0 (0 – 2)

Vasoactive-inotropic score (day 1)

0 (0 – 10)

Vasoactive-inotropic score (day 2)

0 (0 – 6.3)

Need for renal replacement therapy

5 (7.1%)

MODSc (day1)

20 (28.6%)

MODS (day 3)

16 (22.9%)

PICUd stay, days

7 (5 – 12.3)

PIM2e mortality risk%

2.6 (1.6 – 8.5)

pSOFAf score (1st day)

5 (4 – 8.5)

Laboratory values on admission

CRPg, mg/dL

24 (6 – 66)

Hemoglobin, g/dL

10.2 (9.4 – 11.2)

WBCh, 1000/uL

9.2 (4.9 – 14.1)

ANCi, 1000/uL

15 (8.4 – 20.9)

Platelets, 1000/uL

312 (158.3 – 377.5)

Creatinine, mg/dL

0.6 (0.4 – 0.8)

ALTj, U/L

24 (16 – 48.8)

ADAMTS-13k, ng/mL

1.30 (0.88 – 3.13)

  1. Data is presented as median (interquartile range) or number (%)
  2. aAcute Respiratory Distress Syndrome
  3. bHospital-acquired infections
  4. cMultiple Organ Dysfunction Syndrome
  5. dPediatric Intensive Care Unit
  6. ePediatric Index of Mortality2
  7. fpediatric Sequential Organ Failure Assessment score
  8. gC-reactive protein
  9. hWhite blood cell Count
  10. iAbsolute neutrophil count
  11. jAlanine aminotransferase
  12. ka disintegrin-like and metalloprotease with thrombospondin type 1 motif, 13
  13. lDefined as chronic diseases that result in medical fragility, functional limitations, and substantial health care needs