Characteristics | Routine care group (n = 20) | Montelukast group (n = 20) | P value |
---|---|---|---|
Gestational age (weeks)b | 34.85 ± 1.14 | 34.55 ± 0.95 | 0.370 |
Birth weight (grams)b | 1655.5 ± 77.77 | 1688.5 ± 104.74 | 0.258 |
Male (sex)a | 12 (60%) | 8 (40%) | 0.343 |
Postnatal age (days)b | 5.30 ± 2.60 | 5.20 ± 2.51 | 0.902 |
Site of infectiona | 0.694 | ||
Bacteremia | 11 | 10 | |
Pneumonia | 7 | 8 | |
Meningitis | 2 | 1 | |
Septic arthritis | 0 | 1 | |
Respiratory distressa | 9 (45%) | 7 (35%) | 0.748 |
Temperature instabilitya | 8 (40%) | 14 (70%) | 0.11 |
Poor activitya | 14 (70%) | 12 (60%) | 0.74 |
WBCs (109/l)b | 12.13 ± 5.26 | 10.19 ± 5.13 | 0.244 |
Platelet (109/l)b | 110.75 ± 44.13 | 112.45 ± 42.24 | 0.902 |
Serum C-reactive protein (mg/L)c | 96 (24–96) | 96 (24–96) | 0.599 |
INRb | 1.14 ± 0.26 | 1.08 ± 0.14 | 0.426 |
Blood glucose (mg/dL)b | 136.65 ± 44.82 | 127.15 ± 58.71 | 0.569 |
TNF alpha (pg/dL)b | 153.05 ± 50.47 | 167.57 ± 41.78 | 0.328 |
Serum Creatinine (mg/dL)b | 0.53 ± 0.36 | 0.41 ± 0.23 | 0.233 |
AST (IU/L)b | 18.51 ± 7.43 | 22.34 ± 12.23 | 0.240 |
ALT (IU/L)b | 16.60 ± 7.68 | 20.18 ± 11.66 | 0.257 |
PELOD score on admissionc | 0 (0–10) | 0 (0–11) | 0.513 |