Table 3 Risk factors for persistence of wheezing in preschoolers

Consanguinity

15(37.5%)

25(62.5%)

0.82

–

Male gender

24 (38.7%)

38 (61.3%)

0.98

–

Familial atopy

29 (58%)

21 (42%)

0.0018

4.44 [1.74–11.33]

Maternal atopy

15 (62.5%)

9 (37.5%)

0.0077

3.69 [1.41–9.67]

Familial allergic asthma

17(65.51%)

10 (34.49%)

0.0018

4.58 [1.76–11.91]

Familial allergic rhinitis

11 (73.33%)

4 (26.66%)

0.0028

6.46 [1.9–21.96]

Passive smoking

26 (59.1%)

18(40.9%)

 < 0.001

5.05 [2.09–12.17]

Non-exclusive breastfeeding during the first 6 months of life

37 (%)

42 (%)

0.82

–

Proteins of cow’s milk before 2 months old

22 (53.65%)

19 (46.35%)

0.033

2.47 [1.07–5.69]

Age at the 1st episode < 6 months

18 (58.06%)

13 (41.94%)

0.009

3.25 [1.34–7.88]

Two asthma attacks or more with a PRAM score more than 8 during the 4th year of live

5 (83.3%)

1(16.7%)

0.031

3.25 [0.92–428.77]

Moderate persistent asthma

10 (62.5%)

6 (37.5%)

0.039

3.21 [1.05–9.75]

Partly controlled asthma

18 (66.66%)

9 (33.33%)

0.019

5.1 [1.96–13.22]

Inhaled corticosteroids during the first 3 years of life

37 (38.94%)

58 (61.06%)

0.196

–

Aero sensitization

31 (65.3%)

21 (34.7%)

 < 0.001

6.11 [2.26–16.52]

Food sensitization

2 (40%)

3 (60%)

0.95

–