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Table 7 Frequency of NOD2 rs2066845 genotype and allelic polymorphisms among studied asthmatic cases

From: Evaluation of serum levels of interferon beta and nucleotide binding and oligomerization domain 2 gene polymorphism in children with cough asthma phenotype: a case–control study

 

Genotypes

MC

(P)

Allele frequency

χ2

(P)

CC

GC

GG

C

GT

Gender

   

(0.589)

  

0.78

    Male (65)

2 (3.1)

13 (20)

50 (76.9)

 

17(13.1)

113(86.9)

(0.37)

    Female (34)

0 (0)

6 (17.6)

28 (82.4)

 

6 (8.8)

62 (91.2)

 

Family history

   

(0.427)

  

1.8 (0.17)

    Positive (19)

0 (0)

2 (10.5)

17 (89.5)

 

2 (5.3)

36 (94.7)

 

    Negative (80)

2 (2.5)

17(21.2)

61 (76.2)

 

21(13.1)

139(86.9)

 

Parental smoking

   

(0.60)

  

0.91

    Positive (51)

2 (3.9)

10(19.6)

39 (76.5)

 

14(13.7)

88 (86.3)

(0.34)

    Negative (48)

0 (0)

9 (18.8)

39 (81.2)

 

9 (9.4)

87 (90.6)

 

Allergic rhinitis

   

(0.26)

  

1.49

    Positive (59)

0 (0)

11(18.6)

48 (81.4)

 

11 (9.3)

107(90.7)

(0.22)

    Negative (40)

2 (5.0)

8 (20.0)

30 (75.0)

 

12 (15)

68 (85)

 

Atopic dermatitis

   

(0.126)

  

3.78

    Positive (49)

0 (0)

7 (14.3)

42 (85.7)

 

7 (7.1)

91 (92.9)

(0.051)

    Negative (50)

2 (4.0)

12 (24)

36 (72.0)

 

16 (16)

84 (84)