Table 4 Association between laboratory biomarkers and degree of asthma severity and degree of asthma control in different phenotypes (allergic march and cough phenotypes)
Groups | Serum eosinophilic percentage | Serum IgE | Serum IFN-B | ||||
|---|---|---|---|---|---|---|---|
Median (min–max) | P value | Median (min–max) | P value | Median (min–max) | P value | ||
Asthma severity | |||||||
Allergic march | Mild asthma | 5.64 (1.17–10.53) | KW = 2.7 P = 0.26 | 76 (3.30–532) | KW = 5 P = 0.08 | 18.80 (5.70–41.30) | KW = 0.62 P = 0.73 |
Moderate asthma | 5.08 (0.53–13.04) | 181 (6.20–500) | 20.20 (8.35–64.00) | ||||
Severe asthma | 7.54 (4.14–13.18) | 65.30 (32–154) | 21.40 (11.30–46.80) | ||||
Cough phenotype | Mild asthma | 2.75 (1.69–9.03) | Z = 0.29 P = 0.76 | 440 (42.70–688) | Z = 1.0 P = 0.32 | 11.50 (7.330.8) | Z = 2.1 P = 0.03* |
Moderate asthma | 3.45 (0.01–19.24) | 83.70 (1.36–520) | 21.60 (1.76–109) | ||||
Asthma control | |||||||
Allergic march | Controlled | 4.53 (1.78–10.49)a | KW = 7.45 P = 0.02* | 164.00 (29.40–500.00) | KW = 4.01 P = 0.13 | 18.80 (5.70–62.20) | KW = 1.21 P = 0.54 |
Partially controlled | 5.45 (0.53–8.56) | 231.00 (3.30–532.00) | 23.60 (8.35–64.00) | ||||
Uncontrolled | 6.91 (1.75–13.18)a | 85.10 (6.20–483.80) | 18.20 (9.50–46.90) | ||||
Cough phenotype | Controlled | 2.87 (0.01–19.24) | KW = 2.9 P = 0.23 | 46.00 (3.78–520.00) | KW = 4.1 P = 0.12 | 21.55 (4.43–48.90) | KW = 1.5 P = 0.47 |
Partially controlled | 4.45 (0.01–17.81) | 72.80 (1.36–506) | 21.50 (7.30–109) | ||||
Uncontrolled | 3.31 (0.65–10.55) | 391.00 (10.97–688) | 13.15 (1.76–46) | ||||