Table 1 Comparison of age, anthropometric parameters and peak GH levels after provocation in the 3 studied groups (IGHD, ISS and SGA) (no. = 40)
From: Growth hormone therapy response in children with short stature
Characteristics | IGHD (n = 21) | ISS (n = 8) | SGA (n = 11) | p value |
|---|---|---|---|---|
Initial age (years) | 12.56 ± 2.71 | 13.75 ± 3.52 | 11.34 ± 2.99 | 0.163 |
Initial height (cm) | 129.1 ± 13.62 | 133.95 ± 17.21 | 123.27 ± 15.7 | 0.322 |
Initial height SD | -3.46 ± 0.58 | -3.39 ± 0.56 | -3.42 ± 0.78 | 0.931 |
Initial weight (kg) | 29.57 ± 9.51 | 32.69 ± 12.92 | 26.73 ± 9.54 | 0.531 |
Initial weight SD | -2.56 ± 1.12 | -2.875 ± 1.03 | -2.51 ± 1.061 | 0.704 |
Maternal height (cm) | 153.69 ± 3.65 | 155.25 ± 6.09 | 155.59 ± 5.63 | 0.729 |
Paternal height (cm) | 166.88 ± 6.39 | 163.5 ± 6.46 | 167.77 ± 6.95 | 0.38 |
MPH (cm) | 164.51 ± 7.3 | 164.06 ± 8.31 | 164.7 ± 9.3 | 0.901 |
MPH SD | -0.99 ± 0.398 | -1.07 ± 0.52 | -0.85 ± 0.55 | 0.359 |
Initial bone age (years) | 8.84 ± 3.12 | 10.68 ± 2.095 | 8.3 ± 3.55 | 0.282 |
Peak GH in Clonidine test(ng/ml) | 3.18 ± 1.53 | 12.66 ± 4.14 | 6.34 ± 6.02 | ND |
Peak GH in ITT (ng/ml) | 3.28 ± 1.89 | 10.8 ± 6.24 | 4.89 ± 6.82 | ND |