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Table 2 Comparison of characteristics between case and control groups

From: Consanguinity and childhood acute lymphoblastic leukaemia: a case-control study

 

Cases (%)

Controls (%)

p-value

Odds ratio

Non-consanguineous

123 (63.7%)

107 (55.4)

0.819NS

0.951 (0.621–1.458)

Consanguineous

70 (36.3%)

86 (44.6%)

Non-consanguineous

123 (63.7%)

107 (55.4%)

0.0003

-

3rd-degree consanguinity

58 (30.1%)

47 (24.4%)

4th-degree consanguinity

12 (6.2%)

39 (20.2%)

Non-consanguineous

123 (68%)

107 (69.5%)

0.764

1.073 (0.675–1.706)

3rd-degree consanguinity

58 (32%)

47 (30.5%)

Non-consanguineous

123 (91.1%)

57 (79.9%)

0.009

0.387 (0.187–0.801)

4th-degree consanguinity

12 (8.9%)

20 (20.1%)

  1. NS, not significant. When comparing cases and controls with having third consanguinity and fourth consanguinity, p = 0.0090 and OR = 0.360 (0.165–0.787), which indicates that fourth-degree consanguinity was associated with a decreased risk of leukaemia compared to not having consanguinity or to having a third-degree one