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Table 5 Performance of the studied non-invasive markers in the detection of early (F1–F2) in the studied group

From: Comparative study between liver biopsy and non-invasive biomarkers in assessment of hepatic fibrosis in children with chronic liver diseases

 

Cutoff value

Sens%

Spec%

PPV%

NPV%

AUC

95% CI

APRI

> 0.96

46.4%

91.9%

94.7%

32.2%

0.745

0.71–0.82

M-APRI

>0.16

61.3%

96.5%

97.9%

40.4%

0.831

0.63–0.88

FIB-4

>0.019

54.8%

94.5%

97.7%

36.9%

0.750

0.55–0.85

M-FIB-4

>0.005

49.7%

96.5%

97.4%

34.4%

0.759

0.64–0.79

B-AST

>−8

74.2%

75.7%

90.5%

43.2%

0.758

0.66–0.85

  1. Sens sensitivity, Spec specificity, PPV positive predictive value, NPV negative predictive value, AUC area under the curve, CI confidence interval