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Table 2 Comparison between patients with normal and elevated leptin levels

From: Serum Leptin in Hospitalized Community-Acquired Pneumonia Children under the Age of Five Years

 

Normal leptin level (n = 47)

High leptin level (n = 35)

P value

Sex

 Male

31 (66.0%)

23 (65.7%)

0.982c

 Female

16 (34.0%)

12 (34.3%)

 

Age

12.0 (8.0–48.0)a

12.0 (8.0–36.0)a

0.922d

Growth percentile#

 < 5th percentile

3 (6.4%)

2 (5.7%)

1.000c

 5th to less than 85th percentile

35 (74.5%)

26 (74.3%)

 85th to less than 95th percentile

5 (10.6%)

4 (11.4%)

 95th percentile

4 (8.5%)

3 (8.6%)

Respiratory distress

 RD I

0 (0.0%)

0 (0.0%)

< 0.001*c

 RD II

30 (63.8%)

10 (28.6%)

 RD III

17 (36.2%)

18 (51.4%)

 RD IV

0 (0.0%)

7 (20.0%)

Pneumonia severity

 Moderate

36 (76.6%)

17 (48.6%)

0.009*c

 Severe

11 (23.4%)

18 (51.4%)

CRP (mg/L)

10.0 (6.0–18.0)a

149.0 (110.0–190.0)a

< 0.001*d

Sputum culture positive

11 (23.4%)

30 (85.7%)

< 0.001*c

Organisms in sputum

 No growth

44 (93.6%)

9 (25.7%)

< 0.001*c

 Single organism

3 (6.4%)

14 (40.0%)

 More than one organism

0 (0.0%)

12 (34.3%)

Organisms in sputum

 Acinetobacter

3 (6.4%)

5 (14.3%)

0.277c

 Klebsiella

4 (8.5%)

20 (57.1%)

< 0.001*c

 Pseudomonas

5 (10.6%)

18 (51.4%)

< 0.001*c

Admission

 Ward

35 (74.5%)

6 (17.1%)

< 0.001*c

 PICU

12 (25.5%)

29 (82.9%)

 

Needed mechanical ventilation

4 (8.5%)

11 (31.4%)

0.008*c

Duration of mechanical ventilation (days)

7.3 ± 3.3b

6.5 ± 1.2b

0.703e

Hospital stay (days)

11.0 (8.0–14.0)a

15.0 (11.0–19.0)a

< 0.001*d

Mortality

0 (0.0%)

3 (8.6%)

0.074c

  1. aMedian (IQR)
  2. bMean ± SD
  3. cPearson’s Chi square test for independence/Fisher’s exact test
  4. dMann-Whitney test
  5. eStudent’s t test
  6. *Significant at p < 0.05
  7. #Calculated from body weight to length in patients less than 24 months old and from body mass index in those aged 24 months or older [7]