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Table 3 The relation between the presence of antibiotic resistance genes by PCR and the results of disc diffusion antimicrobial susceptibility test for carbapenems and colistin by standard microbiological tests

From: Klebsiella infections in a pediatric intensive care unit: incidence, antimicrobial susceptibility, and resistance genes

Resistant genes

Carbapenems resistance

Colistin resistance

S (n = 17)

R (n = 9)

S (n = 20)

R (n = 6)

No.

%

No.

%

No.

%

No.

%

CTX-M (n = 15)

10

66.7

5

33.3

11

73.3

4

26.7

χ2(p)

0.026 (FEp=1.000)

1.262 (FEp=0.356)

IMP (n = 1)

1

100.0

0

0.0

1

100.0

0

0.0

χ2 (p)

0.551 (FEp=1.000)

0.248 (FEp=1.000)

KPC (n = 1)

1

100.0

0

0.0

1

100.0

0

0.0

χ2 (p)

0.551 (FEp=1.000)

0.248 (FEp=1.000)

NDM (n = 17)

12

70.6

5

29.4

13

76.5

4

23.5

χ2 (p)

0.588 (FEp=0.667)

0.584 (FEp=0.628)

OXA-48-like (n = 3)

1

33.3

2

66.7

2

66.7

1

33.3

χ2 (p)

1.539 (FEp=0.268)

0.434 (FEp=0.488)

VIM (n = 1)

1

100.0

0

0.0

0

0.0

1

100.0

χ2 (p)

0.551 (FEp=1.000)

4.368 (FEp=0.192)

  1. χ2 chi-square test, FE Fisher’s exact, S susceptible, R resistant, CTX-M cefotaximase, IMP imipenemases, KPC Klebsiella pneumonaie carbapenemases, NDM, New-Delhi, M, OXA oxacillinase, VIM veronem integron M