From: Feeding: the hidden variable affecting prognosis of critically ill children
Variable | Early enteral nutrition (≤ 48 h) [n=69] | Late enteral nutrition (> 48 h) [n=126] | P-value |
---|---|---|---|
Age, months | 36 (7–91) | 18 (7.5–60) | 0.11 |
Weight, kg | 13 (6–20) | 10 (6–16) | 0.24 |
Body mass index | 15.6 (13.5–17.7) | 15.6 (14.2–18.2) | 0.62 |
Male sex | 33 (47.8%) | 60 (47.6%) | 0.98 |
Malnutrition | 17 (24.6%) | 37 (29.4%) | 0.48 |
Complex chronic condition | 31 (44.9%) | 60 (47.6%) | 0.72 |
Sepsis on admission | 29 (42%) | 58 (46%) | 0.62 |
Admission pSOFAascore | 4 (3–6) | 5.5 (4–7) | 0.004* |
PNbgiven | 10 (14.5%) | 107 (84.9%) | <0.001* |
PICUcMortality | 1 (1.4%) | 21 (16.7%) | 0.001* |
PICU stay, days | 4 (3–8) | 11.5 (6.8–18) | <0.001* |
ARDSd | 0 (0%) | 3 (2.4%) | 0.55 |
Mechanical ventilation | 3 (4.3%) | 56 (44.4%) | <0.001* |
Mechanical ventilation duration, days | 0 (0–0) | 0 (0–6) | <0.001* |
Vasoactive medication use | 11 (15.9%) | 37 (29.4%) | 0.037* |
Vasoactive infusion days | 0 (0–0) | 0 (0–1.3) | 0.023* |
Hospital-acquired infections | 12 (17.4%) | 50 (39.7%) | 0.001* |
Hospital-acquired infection type | |||
 VAPe | 0 (0%) | 9 (7.1%) | 0.001* |
 CLABSIf | 5 (7.2%) | 32 (25.4%) | |
 VAP+CLABSI** | 0 (0%) | 5 (4%) | |
 Others*** | 7 (10.1%) | 4 (3.2%) | |
Central venous catheter days | 0 (0–0) | 7 (0–14.5) | <0.001* |
Enteral feeding intolerance | 8 (11.6%) | 26 (20.6%) | 0.10 |
Full enteral caloric intake reached | 62 (89.9%) | 104 (82.5%) | 0.17 |
Time to full enteral caloric intake, days | 1 (1–2) | 4 (2.3–6) | <0.001* |