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Table 2 Comparison between normoalbuminuric and microalbuminric patients regarding duration of diabetes, diabetic history, comorbidities, and laboratory findings

From: Urinary N-Acetyl-β-D glucosaminidase (uNAG) levels as an early marker for diabetic nephropathy in children with type 1 diabetes

Characteristics

Diabetics

P value

Group 1

n = 30

Group 2

n = 30

Duration of DM (years)

5 ± 1.8

7.6 ± 2.2

< 0.001

Consanguinity

 Negative

15 (50)

18 (60)

0.18

 Positive

15 (50)

12 (40)

Family history

 Negative

14 (47)

15 (50)

0.25

 Positive

16 (53)

15 (50)

Perinatal history

 Normal

26 (87)

25 (83)

0.13

 NICU

4 (13)

5 (17)

Honeymoon

 No

16 (53)

16 (53)

> 0.99

 Yes

14 (47)

14 (47)

Admission

 PICU

15 (50)

13 (43)

0.61

 Ward

15 (50)

17 (57)

Compliance of measurements

 No

12 (40)

17 (57)

0.20

 Yes

18 (60)

13 (43)

Infection

10 (33)

23 (77)

0.001

Celiac disease

0 (0)

3 (10)

0.24

Other diseases hypothyroidism

2 (7)

2 (7)

< 0.99

IBD

1 (3)

0 (0)

Lipodystrophy

13 (43)

15 (50)

0.61

Hypoglycemia

16 (53)

13 (43)

0.44

Hypertension

0 (0)

7 (23)

0.011

Neuropathy

11 (37)

12 (40)

0.8

Retinopathy

12 (40)

10 (33)

0.6

Nephropathy

0 (0)

30 (100)

< 0.001

Arthropathy

11 (37)

15 (50)

0.3

HbA1c (%)

8.8 ± 1.5

11.2 ± 1.8

< 0.001

Cholesterol (mg/dL)

Mean ± SD

165.4 ± 19.6

170.8 ± 30.5

0.42

Triglycerides (mg/dL)

Median (range)

95 (42–176)

64.5 (12–161)

0.002

LDL (mg/dL)

97.4 ± 23.7

103.4 ± 39.5

0.48

HDL (mg/dL)

48.1 ± 11.4

57.7 ± 16

0.010

ALT (IU/L)

22 ± 8.9

23 ± 12

0.72

AST (IU/L)

24.6 ± 14

24.63 ± 12

0.99

Serum creatinine (mg/dL)

0.82 ± 0.14

0.93 ± 0.18

0.006

uACR (mg/g)

6.2 ± 1.8

73.2 ± 27.9

< 0.001*

Free T4 (ng/dL)

1.4 (0.6–21.6)

1.3 (0.8–17.1)

0.95

TSH (μIU/mL)

1.9 (0.5–8.2)

1.7 (0.35–7.4)

0.59

  1. Data were presented as mean ± standard deviation, number (percentage) and median (interquartile range)
  2. HbA1c Glycosylated hemoglobin, LDL Low-density lipoprotein, HDL High-density lipoprotein, ALT Alanine transaminase, AST Aspartate transaminase, uACR Urinary albumin creatinine ratio, Free T4 Free thyroxin, TSH Thyroid stimulating hormone
  3. *Significant as p value < 0.05