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Table 5 Parameters of diuretic response in the different patients groups

From: Serum chloride and serum sodium derangements in children on prolonged furosemide therapy and their effect on diuretic response

 

Hyponatremia

Hypochloremia

Both

Normal

P value

Sig.

No. = 15

No. = 9

No. = 12

No. = 9

Day 1 weight

Mean ± SD

4.33 ± 1.57

8.63 ± 5.12

5.69 ± 2.19

5.75 ± 2.10

0.061

NS

Range

2.3–7

3–15

4–10

4–10

Day 3 weight

Mean ± SD

3.64 ± 1.51

8.15 ± 5.16

5.26 ± 2.12

5.00 ± 2.13

0.058

NS

Range

2–6.3

2.3–14.5

3.5–9.5

3.5–9.6

Change in body weight

Mean ± SD

0.69 ± 0.26

0.48 ± 0.21

0.43 ± 0.14

0.75 ± 0.22

0.038

S

Range

0.2–1

0.2–0.7

0.2–0.5

0.2–1

Cumulative furosemide dose (mg)

Median

(IQR)

28.9 (17.3–38.5)

97.75 (61.06–120.85)

88 (65.3–99.6)

38.95 (29–47.73)

0.000

HS

Range

11.9–57

45.12–123.2

53.6–106.4

23.4–62

Change in body weight/total diuretic dose

Median

(IQR)

0.51 (0.19–0.69)

0.093 (0.008–0.215)

0.005 (0.004–0.108)

0.385 (0.135–0.515)

0.002

HS

Range

0.027–1

0.001–0.26

0.003–0.25

0.018–0.63