The influence of vitamin D administration on the clinical presentation, body mass index, and osteoprotegerin (OPG) level in a sample of Egyptian children with familial Mediterranean fever

Abdallah, Hanaa Reyad; Thomas, Manal Micheal; Abuelhamd, Walaa Alsharany; Ashour, Adel Mohamed; Youness, Eman Refaat; El-Hariri, Hazem Mohamed; El-Bassyouni, Hala Tabie

doi:10.1186/s43054-021-00091-x

Egyptian Pediatric Association Gazette

Table 5 Comparison between ZBMI, OPG, and vitamin D serum levels according to different demographic and molecular characteristics

From: The influence of vitamin D administration on the clinical presentation, body mass index, and osteoprotegerin (OPG) level in a sample of Egyptian children with familial Mediterranean fever

Condition		Lab	Male	Female	^p
Sex	Before	ZBMI	− 0.3 ± 1.1	0.0 ± 1.5	0.639
		OPG	281.3 ± 67.0	384.7 ± 194.3	0.066
		Vitamin D	21.1 ± 8.8	23.7 ± 10.0	0.429
	After	ZBMI	0.0 ± 1.1	0.4 ± 1.3	0.363
		OPG	638.8 ± 154.5	724.2 ± 216.8	0.197
		Vitamin D	38.8 ± 9.3	43.9 ± 11.4	0.170
	Change	ZBMI	0.2 ± 0.5	0.4 ± 1.0	0.548
		OPG	357.5 ± 162.1	317.6 ± 252.4	0.587
		Vitamin D	17.7 ± 7.3	20.2 ± 7.0	0.344
Molecular diagnosis			M694I	M694I + M680I
	Before	ZBMI	− 0.1 ± 1.4	− 0.4 ± 1.0	0.561
		OPG	327.1 ± 145.6	308.5 ± 117.2	0.738
		Vitamin D	22.3 ± 7.8	20.0 ± 10.8	0.516
	After	ZBMI	0.2 ± 1.3	0.2 ± 0.9	0.967
		OPG	688.0 ± 188.7	672.5 ± 170.0	0.834
		Vitamin D	42.5 ± 9.3	35.6 ± 9.0	0.072
	Change	ZBMI	0.3 ± 0.7	0.6 ± 0.8	0.353
		OPG	345.2 ± 225.4	364.0 ± 172.8	0.825
		Vitamin D	20.2 ± 6.9	15.6 ± 8.1	0.127
Consanguinity			Present	Absent
	Before	ZBMI	− 0.4 ± 0.6	− 0.1 ± 1.4	0.354
		OPG	354.1 ± 204.5	320.0 ± 127.9	0.668
		Vitamin D	19.2 ± 6.8	23.3 ± 9.9	0.293
	After	ZBMI	− 0.3 ± 1.1	0.3 ± 1.2	0.294
		OPG	660.3 ± 162.7	683.2 ± 197.3	0.768
		Vitamin D	39.3 ± 10.0	41.7 ± 10.7	0.571
	Change	ZBMI	0.2±1.0	0.4 ± 0.7	0.559
		OPG	306.2 ± 135.2	350.0 ± 224.7	0.607
		Vitamin D	20.1 ± 8.5	18.5 ± 6.8	0.591
Family history			Present	Absent
	Before	ZBMI	− 0.4 ± 1.4	− 0.1 ± 1.2	0.569
		OPG	299.2 ± 126.6	347.2 ± 159.3	0.369
		Vitamin D	23.8 ± 11.3	21.3 ± 7.9	0.449
	After	ZBMI	0.2 ± 1.2	0.2 ± 1.2	0.977
		OPG	574.5 ± 153.5	744.7 ± 179.5	0.008*
		Vitamin D	39.3 ± 11.9	42.3 ± 9.5	0.421
	Change	ZBMI	0.6 ± 0.9	0.2 ± 0.7	0.316
		OPG	275.3 ± 114.8	381.1 ± 241.2	0.102
		Vitamin D	15.4 ± 5.9	21.1 ± 7.2	0.025*

^Independent t test. *Significant

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