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Table 1 Baseline demographic, clinical, and laboratory characteristics of cases and controls

From: Metabolic and inflammatory biomarkers in children with atopic dermatitis (AD): a case-control study

  Controls Cases P value
N = 101 N = 100
Gender    < 0.001
Males 63 (62.4%) 39 (39.0%)  
Females 38 (37.6%) 61 (61.0%)  
Age (years) 9.2 ± 3.3 11.0 ± 2.7 < 0.001
Age categories    < 0.001
Children 78 (77.2%) 53 (53.0%)  
Adolescents 23 (22.8%) 47 (47.0%)  
BMI 26.1 ± 4.9 34.7 ± 5.7 < 0.001
BMI for age and gender    < 0.001
Normal 14 (13.9%) 0 ( 0.0%)  
Overweight 52 (51.5%) 19 (19.0%)  
Obese 35 (34.7%) 81 (81.0%)  
Fasting glucose (mg/dL) 100.8 ± 16.0 143.2 ± 30.3 < 0.001
Diabetes    < 0.001
Normal 63 (62.4%) 6 (6.0%)  
Prediabetes 32 (31.7%) 25 (25.0%)  
Diabetes 6 (5.9%) 69 (69.0%)  
Insulin (mIU/L) 4.6 ± 3.0 11.3 ± 4.4 < 0.001
CRP (mg/L) 5.1 ± 3.4 19.9 ± 13.2 < 0.001
CRP categories    < 0.001
Normal 95 (94.1%) 18 (18.0%)  
Elevated 6 ( 5.9%) 82 (82.0%)  
IgE 252.7 ± 103.1 2050.3 ± 843.8 < 0.001
IgE categories    < 0.001
Normal 93 (92.1%) 5 (5.0%)  
Elevated 8 ( 7.9%) 95 (95.0%)  
Serum triglycerides (mg/dL) 156.2 ± 31.6 194.1 ± 38.1 < 0.001
Triglycerides categories    < 0.001
Normal 51 (50.5%) 5 ( 5.0%)  
Borderline high 32 (31.7%) 58 (58.0%)  
High 18 (17.8%) 37 (37.0%)  
Cholesterol (mg/L) 163.7 ± 27.7 198.4 ± 27.7 < 0.001
Cholesterol categories    < 0.001
Normal 96 (95.0%) 66 (66.0%)  
Borderline high 2 ( 2.0%) 21 (21.0%)  
High 3 ( 3.0%) 13 (13.0%)  
Alkaline phosphatase (U/L) 189.4 ± 46.8 229.4 ± 89.8 < 0.001
Alkaline phosphatase categories    0.67
Normal 87 (86.1%) 84 (84.0%)  
Elevated 14 (13.9%) 16 (16.0%)  
GGT (IU/L) 34.3 ± 9.5 54.7 ± 19.9 < 0.001
GGT categories    < 0.001
Normal 54 (53.5%) 17 (17.0%)  
Elevated 47 (46.5%) 83 (83.0%)