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Table 1 Baseline demographic, clinical, and laboratory characteristics of cases and controls

From: Metabolic and inflammatory biomarkers in children with atopic dermatitis (AD): a case-control study

 

Controls

Cases

P value

N = 101

N = 100

Gender

  

< 0.001

Males

63 (62.4%)

39 (39.0%)

 

Females

38 (37.6%)

61 (61.0%)

 

Age (years)

9.2 ± 3.3

11.0 ± 2.7

< 0.001

Age categories

  

< 0.001

Children

78 (77.2%)

53 (53.0%)

 

Adolescents

23 (22.8%)

47 (47.0%)

 

BMI

26.1 ± 4.9

34.7 ± 5.7

< 0.001

BMI for age and gender

  

< 0.001

Normal

14 (13.9%)

0 ( 0.0%)

 

Overweight

52 (51.5%)

19 (19.0%)

 

Obese

35 (34.7%)

81 (81.0%)

 

Fasting glucose (mg/dL)

100.8 ± 16.0

143.2 ± 30.3

< 0.001

Diabetes

  

< 0.001

Normal

63 (62.4%)

6 (6.0%)

 

Prediabetes

32 (31.7%)

25 (25.0%)

 

Diabetes

6 (5.9%)

69 (69.0%)

 

Insulin (mIU/L)

4.6 ± 3.0

11.3 ± 4.4

< 0.001

CRP (mg/L)

5.1 ± 3.4

19.9 ± 13.2

< 0.001

CRP categories

  

< 0.001

Normal

95 (94.1%)

18 (18.0%)

 

Elevated

6 ( 5.9%)

82 (82.0%)

 

IgE

252.7 ± 103.1

2050.3 ± 843.8

< 0.001

IgE categories

  

< 0.001

Normal

93 (92.1%)

5 (5.0%)

 

Elevated

8 ( 7.9%)

95 (95.0%)

 

Serum triglycerides (mg/dL)

156.2 ± 31.6

194.1 ± 38.1

< 0.001

Triglycerides categories

  

< 0.001

Normal

51 (50.5%)

5 ( 5.0%)

 

Borderline high

32 (31.7%)

58 (58.0%)

 

High

18 (17.8%)

37 (37.0%)

 

Cholesterol (mg/L)

163.7 ± 27.7

198.4 ± 27.7

< 0.001

Cholesterol categories

  

< 0.001

Normal

96 (95.0%)

66 (66.0%)

 

Borderline high

2 ( 2.0%)

21 (21.0%)

 

High

3 ( 3.0%)

13 (13.0%)

 

Alkaline phosphatase (U/L)

189.4 ± 46.8

229.4 ± 89.8

< 0.001

Alkaline phosphatase categories

  

0.67

Normal

87 (86.1%)

84 (84.0%)

 

Elevated

14 (13.9%)

16 (16.0%)

 

GGT (IU/L)

34.3 ± 9.5

54.7 ± 19.9

< 0.001

GGT categories

  

< 0.001

Normal

54 (53.5%)

17 (17.0%)

 

Elevated

47 (46.5%)

83 (83.0%)