Table 6 Performance of the studied non-invasive biomarkers in the detection of advanced liver fibrosis (F3–F4) in the studied group
Cutoff value | Sens% | Spec% | PPV% | NPV% | AUC | 95% CI | |
|---|---|---|---|---|---|---|---|
APRI | >1.96 | 89.9% | 84.5% | 34.8% | 98.7% | 0.849 | 0.76–0.92 |
M-APRI | >2.2 | 87.8% | 96.6% | 72.7% | 98.9% | 0.958 | 0.92–0.98 |
FIB-4 | >0.045 | 78.8% | 85.6% | 33.3% | 97.5% | 0.853 | 0.77–0.91 |
M-FIB-4 | >0.015 | 89.8% | 82.4% | 32% | 98.7% | 0.896 | 0.84–0.97 |
B-AST | >92.1 | 89.8% | 91.2% | 47.1% | 98.8% | 0.955 | 0.875–0.97 |