Nephrotic syndrome with impaired diastolic function (n = 18) | Nephrotic Syndrome with normal diastolic function (n = 22) | P-value | |
---|---|---|---|
Mean ± SD | Mean ± SD | ||
Serum creatinine at the time of assessment (mg/dL) | 0.79 ± 0.04 | 0.8 ± 0.04 | 0.44 |
Serum urea at the time of assessment (mg/dL) | 14 ± 1.9 | 12 ± 3.1 | 0.65 |
Serum baseline cholesterol (mg/dL) | 229 ± 11 | 231 ± 10 | 0.43 |
Serum cholesterol at the time of assessment (mg/dL) | 175 ± 193 | 175 ± 19 | 0.78 |
Serum baseline albumin (gm/dL) | 2.1 ± 0.2 | 2.2 ± 0.2 | 0.59 |
Serum albumin at the time of assessement (gm/dL) | 2.4 ± 0.2 | 2.8 ± 0.1 | < 0.001 |
Baseline urine P/C ratio | 6 ± 0.8 | 5.2 ± 0.5 | 0.68 |
Urine P/C ratio at the time of assessment | 2.9 ± 0.6 | 1.5 ± 0.3 | < 0.001 |
Duration from onset of NS to time of assessment by echocardiography (weeks) | 14.9 ± 2 | 15.9 ± 1 | 0.07 |
Duration of steroid therapy (weeks) | 15 ± 2 | 12 ± 1 | 0.44 |
Dose of steroid | 2 ± 0 | 2 ± 0 | 0.78 |
Weight difference from the onset to time of assessment (kg) | 2.3 ± 0.3 | 3.1 ± 0.3 | < 0.001 |
3D LVEDV (ml) | 60 ± 8 | 59 ± 13 | 0.42 |
3D EF (%) | 78 ± 2.5 | 79 ± 3.1 | 0.33 |
FS (%) | 46 ± 3 | 46 ±2 | 0.39 |
GLS (%) | 15 ± 3.2 | 19 ± 1.41 | < 0.0001 |
E/e′ | 13±3 | 8±2 | < 0.0001 |