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Table 2 Comparison of clinical data, thyroid function, lipid profile, and oxidative DNA damage in relation to subclinical hypothyroidism in children with obesity

From: Oxidative DNA damage and subclinical hypothyroidism in children with obesity

  Obese children with subclinical hypothyroidism
N=17
Obese children without subclinical hypothyroidism
N=33
Independent t test/Mann-Whitney test
Mean±SD Mean±SD t p-value
Age (year) 7.294±0.848 7.212±.0781 0.332 0.742
Weight (kg) 53.058±10.346 45.666±9.771 2.438 0.021*
Height (cm) 135.352±9.212 129.666±9.681 2.032 0.052
BMI 28.619±2.768 26.777±2.514 2.298 0.029*
HC (cm) 101.205±10.410 97.048±5.204 1.550 0.137
WC (cm) 89.529±9.663 80.272±7.446 3.456 0.002*
Hip/waist ratio 0.874±0.041 0.833±0.067 2.708 0.009*
Triglyceride (mg/dl) 94.00±7.558 89.606±6.777 2.016 0.053
Cholesterol (mg/dl) 147.352±22.312 147.545±23.285 −0.028 0.977
HDL (mg/dl) 52.529±14.820 48.272±7.045 1.121 0.276
TSH (μIU/ml) 8.911±0.572 3.630±1.908 14.671 0.0001*
T4 (μg/dl) 4.917±1.308 5.675±1.970 −1.622 0.112
T3 (μg/dl) 0.876±0.562 1.006±0.501 −0.800 0.430
TPO AB (IU/ml) 67.553±15.937 75.334±8.083 −1.892 0.073
TG AB (IU/ml) 25.388±11.048 27.818±9.221 −0.778 0.443
8-OHdG (pg/ml) 1652.97±1185.96 2130.772±1475.766 −1.239 0.223
  1. HC hip circumference, WC waist circumference, HDL high-density lipoprotein, TPO thyroid peroxidase antibody, TG anti-thyroglobulin antibodies, 8-OHdG 8-hydroxydeoxyguanosine
  2. *Significant (p-value < 0.05)