Table 2 Comparison of clinical data, thyroid function, lipid profile, and oxidative DNA damage in relation to subclinical hypothyroidism in children with obesity
From: Oxidative DNA damage and subclinical hypothyroidism in children with obesity
Obese children with subclinical hypothyroidism N=17 | Obese children without subclinical hypothyroidism N=33 | Independent t test/Mann-Whitney test | ||
|---|---|---|---|---|
Mean±SD | Mean±SD | t | p-value | |
Age (year) | 7.294±0.848 | 7.212±.0781 | 0.332 | 0.742 |
Weight (kg) | 53.058±10.346 | 45.666±9.771 | 2.438 | 0.021* |
Height (cm) | 135.352±9.212 | 129.666±9.681 | 2.032 | 0.052 |
BMI | 28.619±2.768 | 26.777±2.514 | 2.298 | 0.029* |
HC (cm) | 101.205±10.410 | 97.048±5.204 | 1.550 | 0.137 |
WC (cm) | 89.529±9.663 | 80.272±7.446 | 3.456 | 0.002* |
Hip/waist ratio | 0.874±0.041 | 0.833±0.067 | 2.708 | 0.009* |
Triglyceride (mg/dl) | 94.00±7.558 | 89.606±6.777 | 2.016 | 0.053 |
Cholesterol (mg/dl) | 147.352±22.312 | 147.545±23.285 | −0.028 | 0.977 |
HDL (mg/dl) | 52.529±14.820 | 48.272±7.045 | 1.121 | 0.276 |
TSH (μIU/ml) | 8.911±0.572 | 3.630±1.908 | 14.671 | 0.0001* |
T4 (μg/dl) | 4.917±1.308 | 5.675±1.970 | −1.622 | 0.112 |
T3 (μg/dl) | 0.876±0.562 | 1.006±0.501 | −0.800 | 0.430 |
TPO AB (IU/ml) | 67.553±15.937 | 75.334±8.083 | −1.892 | 0.073 |
TG AB (IU/ml) | 25.388±11.048 | 27.818±9.221 | −0.778 | 0.443 |
8-OHdG (pg/ml) | 1652.97±1185.96 | 2130.772±1475.766 | −1.239 | 0.223 |