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Table 1 Comparison of thyroid function, lipid profile, and oxidative DNA damage between children with obesity and healthy controls

From: Oxidative DNA damage and subclinical hypothyroidism in children with obesity

 

Healthy children

N=40

Obese children

N=50

Independent t test/Mann-Whitney test

Mean±SD

Mean±SD

t

p-value

TSH (μIU/ml)

2.125±1.405

5.426±2.978

−6.931

<0.0001*

T4 (μg/dl)

7.810±2.771

5.418±1.796

4.722

<0.0001*

T3 (μg/dl)

1.377±0.502

0.962±0.521

3.834

<0.0001*

TPO AB (IU/ml)

79.435±18.691

72.689±11.810

1.987

0.055

TG AB (IU/ml)

23.562±11.015

26.992±9.835

−1.539

0.128

8-OHdG (pg/ml)

1732.01±1083.67

1968.32±1390.62

−0.906

0.367

  1. TSH thyroid-stimulating hormone, TPO thyroid peroxidase antibody, TG anti-thyroglobulin antibodies, 8-OHdG 8-hydroxydeoxyguanosine
  2. *Significant (p-value <0.05)