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Table 1 Comparison of thyroid function, lipid profile, and oxidative DNA damage between children with obesity and healthy controls

From: Oxidative DNA damage and subclinical hypothyroidism in children with obesity

  Healthy children
N=40
Obese children
N=50
Independent t test/Mann-Whitney test
Mean±SD Mean±SD t p-value
TSH (μIU/ml) 2.125±1.405 5.426±2.978 −6.931 <0.0001*
T4 (μg/dl) 7.810±2.771 5.418±1.796 4.722 <0.0001*
T3 (μg/dl) 1.377±0.502 0.962±0.521 3.834 <0.0001*
TPO AB (IU/ml) 79.435±18.691 72.689±11.810 1.987 0.055
TG AB (IU/ml) 23.562±11.015 26.992±9.835 −1.539 0.128
8-OHdG (pg/ml) 1732.01±1083.67 1968.32±1390.62 −0.906 0.367
  1. TSH thyroid-stimulating hormone, TPO thyroid peroxidase antibody, TG anti-thyroglobulin antibodies, 8-OHdG 8-hydroxydeoxyguanosine
  2. *Significant (p-value <0.05)