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Table 1 Characteristics of patients’ groups

From: B-natriuretic peptide serum levels in neonates with persistent pulmonary hypertension

Variable Mild (11 patients) Moderate (14 patients) Severe (5 patients) p-value
Gestational age (weeks)a 38.2 ± 0.8 37.7 ± 0.7 37.7 ± 0.5 0.6
Birth weight (grams)a 2904 ± 170 2932 ± 200 2893 ± 150 0.3
Gender (male/female)b 7/4 10/5 4/0 0.2
Mode of delivery (vaginal/cesarean section)b 7/4 8/6 3/2 0.7
Age of mothers (years)a 24.1 ± 3.2 23.8 ± 2.9 23.4 ± 4.1 0.5
Pulmonary artery pressure (mm Hg)c 48 (45–50) 55 (53–57) 65 (64–79) 0.001
Oxygenation index (OI)c 10.8 (9.6–12.1) 19.7 (16.9–22.3) 31.7(27.9–36.2) 0.001
Response after 4 days of treatmentb
 Remission/no remission 9/2 9/5 2/3 0.1
B-natriuretic peptide serum level (pg/ml)c
 Before treatment 310 (305–330) 350 (340–350) 465 (450–495) 0.001
 After treatment 90 (88–96) 97 (94–99) 105 (98–110) 0.001
  1. aExpressed as mean ± SD
  2. bexpressed as frequency
  3. cexpressed as median (IQR)