From: B-natriuretic peptide serum levels in neonates with persistent pulmonary hypertension
Variable | Mild (11 patients) | Moderate (14 patients) | Severe (5 patients) | p-value |
---|---|---|---|---|
Gestational age (weeks)a | 38.2 ± 0.8 | 37.7 ± 0.7 | 37.7 ± 0.5 | 0.6 |
Birth weight (grams)a | 2904 ± 170 | 2932 ± 200 | 2893 ± 150 | 0.3 |
Gender (male/female)b | 7/4 | 10/5 | 4/0 | 0.2 |
Mode of delivery (vaginal/cesarean section)b | 7/4 | 8/6 | 3/2 | 0.7 |
Age of mothers (years)a | 24.1 ± 3.2 | 23.8 ± 2.9 | 23.4 ± 4.1 | 0.5 |
Pulmonary artery pressure (mm Hg)c | 48 (45–50) | 55 (53–57) | 65 (64–79) | 0.001 |
Oxygenation index (OI)c | 10.8 (9.6–12.1) | 19.7 (16.9–22.3) | 31.7(27.9–36.2) | 0.001 |
Response after 4 days of treatmentb | ||||
Remission/no remission | 9/2 | 9/5 | 2/3 | 0.1 |
B-natriuretic peptide serum level (pg/ml)c | ||||
Before treatment | 310 (305–330) | 350 (340–350) | 465 (450–495) | 0.001 |
After treatment | 90 (88–96) | 97 (94–99) | 105 (98–110) | 0.001 |