Table 3 Comparison between patients who did not receive shock therapy in both groups (0.9% versus 0.45% saline) regarding different laboratory parameters
Laboratory variables | Timing (hours) | Group 1 0.9% NS (N=15) Mean ± SD | Group2 0.45% NS (N=25) Mean ± SD | P value |
|---|---|---|---|---|
PH | 0 | 7.14 ± 0.07 | 7.13 ± 0.06 | 0.60 |
4 | 7.21 ± 0.09 | 7.22 ± 0.05 | 0.62 | |
8 | 7.29 ± 0.09 | 7.26 ± 0.04 | 0.42 | |
12 | 7.32 ± 0.04 | 7.34 ± 0.04 | 0.56 | |
HCO3 (meq/L) | 0 | 8.4 ± 1.6 | 8.02 ± 1.8 | 0.49 |
4 | 10.05 ± 2.8 | 9.41 ± 2.1 | 0.42 | |
8 | 13.3 ± 3.01 | 11.4 ± 1.9 | 0.07 | |
12 | 13.25 ± 2.8 | 12.6 ± 1.3 | 0.67 | |
Serum Na (meq/L) | 0 | 133.8 ± 3.8 | 134 ± 4.2 | 0.85 |
4 | 136.3 ± 5.7 | 135.4 ± 5.3 | 0.62 | |
8 | 136.3 ± 4.6 | 136.3 ± 6.6 | 0.98 | |
Corrected Na (meq/L) | 0 | 141.8 ± 4.7 | 142 ± 4.6 | 0.91 |
4 | 140.8 ± 5.2 | 142.3 ± 5.1 | 0.37 | |
8 | 141.1 ± 6.1 | 136.3 ± 4.6 | 0.40 | |
CL (meq/L) | 0 | 102.4 ± 4.9 | 102.7 ± 4.3 | 0.86 |
4 | 104.7 ± 3.8 | 102.6 ± 3.5 | 0.12 | |
8 | 107.6 ± 4.8 | 103.6 ± 4.2 | 0.08 | |
CL:Na ratio | 0 | 0.77 ± 0.03 | 0.76 ± 0.02 | 0.94 |
4 | 0.76 ± 0.01 | 0.75 ± 0.02 | 0.21 | |
8 | 0.79 ± 0.01 | 0.76 ± 0.03 | 0.007 | |
Anion gap | 0 | 23.6 ± 2.9 | 22.8 ± 2.9 | 0.48 |
4 | 21.4 ± 5.02 | 23.7 ± 4.03 | 0.16 | |
8 | 13.8 ± 2.03 | 11.4 ± 1.9 | 0.000 | |
BHOH | 0 | 4.8 ± 0.94 | 5.32 ± 1.6 | 0.26 |
4 | 3.9 ± 1.1 | 4.2 ± 1.3 | 0.48 | |
8 | 3.07 ± 0.88 | 3.4 ± 1. | 0.43 | |
Hyperchloremia n (%) | 0 | 2 (13.3%) | 2 (8%) | 0.63 |
4 | 2 (13.3%) | 1 (4%) | 0.22 | |
8 | 2 (13.3) | 2 (8%) | 0.63 | |
Duration of DKA resolution (hours) | 9.87 ± 3.58 | 8.80 ± 3.317 | 0.34 | |