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Table 2 The course of PH, HCO3, corrected Na, CL, Cl:Na ratio, capillary BHOB, anion gap, glucose, and effective osmolarity at 4 and 8 h among both groups

From: Outcome of the use of 0.9% saline versus 0.45% saline for fluid rehydration in moderate and severe diabetic ketoacidosis in children

Laboratory variables Timing (hours) Group 1
0.9% NS
(N=72)
Mean ± SD
Group2
0.45% NS (N=49)
Mean ± SD
P value
PH 4 7.16 ± 0.1 7.14 ± 0.13 0.37
8 7.23 ± 0.09 7.20 ± 0.1 0.55
At recovery 7.35 ± 0.04 7.36 ± 0.05 0.21
HCO3 (meq/L) 4 7.34 ± 3.4 6.98 ± 3.18 0.56
8 9.8 ± 3.6 8.8 ± 3.5 0.5
At recovery 16.9 ± 1.37 17.02 ± 1.96 0.82
Serum Na (meq/L) 4 136.28 ± 4.94 135.94 ± 4.64 0.70
8 137.3 ± 5.4 138.4 ± 6.6 0.98
At recovery 140.7 ± 6.5 140.3 ± 5.4 0.69
Corrected Na (meq/L) 4 142 ± 4.8 143.1 ± 4.6 0.18
8 141 ± 6 143.4 ± 6.2 0.12
At recovery 140.7 ± 6.5 140.3 ± 5.4 0.69
CL (meq/L) 4 106.28 ± 5.1 103 ± 3.6 0.002
8 108.4 ± 5.6 104.7 ± 6.1 0.06
CL:Na ratio 4 0.78 ± 0.03 0.76 ± 0.02 0.001
8 0.79 ± 0.02 0.76 ± 0.03 0.000
Anion gap 4 22.8 ± 5.1 26.1 ± 5 0.002
8 18.5 ± 4.5 25.8 ± 5.6 0.000
BHOH 4 4.6 ± 1.1 4.9 ± 1.5 0.97
  8 4.05 ± 1.1 4.09 ± 1.4 0.88
Plasma glucose (mg/dl) 4 389 ± 166 433 ± 145 0.35
8 307.3 ± 134 324.8 ± 124.5 0.51
Effective serum osmolality (mosmol/L) 4 293 ± 12.4 296 ± 12.7 0.21
8 291 ± 12.5 295 ± 13 0.22
Hyperchloremia
n (%)
0 9 (15.3%) 4 (11.1%) 0.4
4 16 (28.6%) 2 (4.9%) 0.002
8 15 (34.9%) 4 (12.5%) 0.02