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Table 2 The course of PH, HCO3, corrected Na, CL, Cl:Na ratio, capillary BHOB, anion gap, glucose, and effective osmolarity at 4 and 8 h among both groups

From: Outcome of the use of 0.9% saline versus 0.45% saline for fluid rehydration in moderate and severe diabetic ketoacidosis in children

Laboratory variables

Timing (hours)

Group 1

0.9% NS

(N=72)

Mean ± SD

Group2

0.45% NS (N=49)

Mean ± SD

P value

PH

4

7.16 ± 0.1

7.14 ± 0.13

0.37

8

7.23 ± 0.09

7.20 ± 0.1

0.55

At recovery

7.35 ± 0.04

7.36 ± 0.05

0.21

HCO3 (meq/L)

4

7.34 ± 3.4

6.98 ± 3.18

0.56

8

9.8 ± 3.6

8.8 ± 3.5

0.5

At recovery

16.9 ± 1.37

17.02 ± 1.96

0.82

Serum Na (meq/L)

4

136.28 ± 4.94

135.94 ± 4.64

0.70

8

137.3 ± 5.4

138.4 ± 6.6

0.98

At recovery

140.7 ± 6.5

140.3 ± 5.4

0.69

Corrected Na (meq/L)

4

142 ± 4.8

143.1 ± 4.6

0.18

8

141 ± 6

143.4 ± 6.2

0.12

At recovery

140.7 ± 6.5

140.3 ± 5.4

0.69

CL (meq/L)

4

106.28 ± 5.1

103 ± 3.6

0.002

8

108.4 ± 5.6

104.7 ± 6.1

0.06

CL:Na ratio

4

0.78 ± 0.03

0.76 ± 0.02

0.001

8

0.79 ± 0.02

0.76 ± 0.03

0.000

Anion gap

4

22.8 ± 5.1

26.1 ± 5

0.002

8

18.5 ± 4.5

25.8 ± 5.6

0.000

BHOH

4

4.6 ± 1.1

4.9 ± 1.5

0.97

 

8

4.05 ± 1.1

4.09 ± 1.4

0.88

Plasma glucose (mg/dl)

4

389 ± 166

433 ± 145

0.35

8

307.3 ± 134

324.8 ± 124.5

0.51

Effective serum osmolality (mosmol/L)

4

293 ± 12.4

296 ± 12.7

0.21

8

291 ± 12.5

295 ± 13

0.22

Hyperchloremia

n (%)

0

9 (15.3%)

4 (11.1%)

0.4

4

16 (28.6%)

2 (4.9%)

0.002

8

15 (34.9%)

4 (12.5%)

0.02