Table 1 Reported cases of vertical transmission, clinical manifestations and placental abnormalities in SARS-1, HKCoV, and MERS
Paper | Jeong et al [1] | Payne et al [2] | Wong et al [3] | Yudin et al [4] | Stockman et al [5] | Gagneur et al [6] | Li et al [7] | Shek et al [8] | Robertson et al [9] | Totals |
|---|---|---|---|---|---|---|---|---|---|---|
Outbreak | MERS | MERS | SARS-1 | SARS-1 | MERS | HKCoV/SARS | SARS-1 | SARS-1 | SARS-1 | |
Number of studied mother-infant pairs | 1 | 1 | 12 | 1 | 2 | 7 | 41 | 5 | 1 | 71 |
Number of neonates with vertical transmission | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 2/71 (2.8%) |
Reported complications in neonates(whether with positive or negative swabs) | 0 | 1: Still birth | 2: NEC 1: RDS | 0 | 0 | 2: Still birth with fetal deceleration | 0 | 2: NEC | 0 | RDS: 1/71 (1.4%) Still birth: Mar-71 − 4.20% NEC: 4/71 (5.6%) |
Reported placental abnormalities | 2: Placental infarction | Not reported | 1: Placental infarction | Not reported | Placenta negative for SARS-CoV, no pathological examination | Not reported | Not reported | Not reported | Not reported | 3/25 (12%) |
Maternal co-morbidities | None | None | None | None | Gestational diabetes in the third trimester | One mother developed eclampsia | None | None | None | Â |