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Table 4 ROC curve analysis for the performance of glucose parameters in early diagnosis of IR

From: Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major

Variable

Sensitivity

Specificity

PPV

NPV

AUC

95% CI

P

Fasting plasma g ≥ 115.5 mg/dl

81.8%

79.3%

60%

92%

0.828

0.68-0.98

0.002 (S)

2 h pp plasma glucose ≥ 162.5 mg/dl

81.8%

62.1%

45%

90%

0.812

0.66-0.96

0.003 (S)

Fasting insulin ≥ 9.13μU/ml

81.8%

72.4%

52.9%

91.3%

0.776

0.58-0.96

0.008 (S)

  1. PPV positive predictive value, NPV negative predictive value, AUC area under the curve, CI confidence interval