Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major

Egyptian Pediatric Association Gazette

Table 3 Correlations between serum glycemic parameters and various parameters in the patient group

With	Serum ferretin (n = 40)		Fasting plasma glucose (n = 40)		Fasting insulin (n = 40)		2 h pp plasma glucose (n = 40)		HOMA-IR (n = 40)
With	Rho	P	Rho	P	Rho	P	Rho	P	Rho	P
Age	0.375	0.017 (S)	0.169	0.29	0.069	0.67	0.029	0.86	0.291	0.068
Duration of blood transfusion	0.181	0.26	0.361	0.022 (S)	0.192	0.23	0.252	0.11	0.481	0.002 (S)
BMI (kg/m²)	0.206	0.20	0.018	0.91	−0.064	0.69	0.096	0.55	0.005	0.97
Liver size	0.008	0.96	0.157	0.33	−0.088	0.59	0.046	0.78	0.031	0.85
Spleen size	0.293	0.075	0.071	0.67	−0.023	0.89	0.033	0.84	−0.051	0.76
Hb	0.019	0.91	0.147	0.36	0.166	0.31	0.244	0.13	0.146	0.37
ALT	0.519	=0.001 (HS)	0.225	0.16	0.149	0.35	0.200	0.21	0.391	0.013 (S)
AST	0.251	0.12	0.120	0.46	0.02	0.90	0.156	0.34	0.124	0.44
Serum ferritin			0.361	0.022 (S)	0.425	0.006 (S)	0.393	0.012 (S)	0.396	0.012 (S)
Fasting plasma glucose	0.361	0.022 (S)			0.315	0.048 (S)			0.473	0.002 (S)
Fasting plasma insulin	0.425	0.006 (S)							0.707	< 0.001 (HS)
2 h pp plasma glucose	0.393	0.012 (S)	0.837	< 0.001 (HS)	0.347	0.028 (S)			0.383	0.015 (S)
HOMA-IR	0.396	0.012 (S)

ALT alanine aminotransferase, AST aspartate aminotransferase, HOMA-IR Homeostasis Model Assessment of insulin resistance index