Table 2 Comparison between thalassemic patients with and without IR according to different variables
From: Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major
No IR (N = 29) | IR (N = 11) | St. “t” | P | |||||
|---|---|---|---|---|---|---|---|---|
Mean | ± SD | Range | Mean | ± SD | Range | |||
Age (years) | 10.8 | 2.44 | 8-16 | 12.5 | 3.09 | 8-16 | 1.82 | 0.076 |
BMI (kg/m2) | 19.6 | 4.69 | 13.6-30.6 | 21.4 | 7.25 | 16.3-40.4 | 0.94 | 0.35 (NS) |
Liver span | 8.75 | 3.98 | 5-19 | 10.00 | 4.07 | 5-15 | 0.76 | 0.44 (NS) |
Spleen size | 3.32 | 2.38 | 0-7 | 4.30 | 3.78 | 0-10 | 0.68 | 0.49 (NS) |
Duration of bl transfusion (years) | 9.38 | 2.50 | 6-15 | 12.55 | 2.75 | 7.9-15.6 | 3.47 | =0.001 (HS) |
Hb% | 8.43 | 1.18 | 6.3-10.0 | 8.62 | 1.11 | 6.5-10.0 | 0.45 | 0.65 (NS) |
ALT(U/L) | 52.0 | 13.5 | 35-93 | 64.7 | 17.1 | 37.5-96 | 2.46 | 0.018 (S) |
AST(U/L) | 49.7 | 8.54 | 35-65 | 57.4 | 18.47 | 36.2-95 | 1.83 | 0.075 |
Serum ferritin (ng/ml) | 2447.2 | 1044.4 | 1103-5426 | 3759.7 | 1617.7 | 1234-6989 | 2.63 | 0.008 (S) |
Fasting plasma glucose | 98.4 | 18.94 | 70-125 | 121.5 | 17.40 | 88-151 | 3.17 | 0.002 (S) |
2 h pp plasma glucose | 146.4 | 26.8 | 99-199 | 184.7 | 29.3 | 144-225 | 3.02 | 0.003 (S) |
Fasting plasma insulin | 7.06 | 3.69 | 2.62-20.66 | 21.34 | 25.64 | 3.34-74.9 | 2.67 | 0.008 (S) |