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Table 2 Comparison between thalassemic patients with and without IR according to different variables

From: Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major

  No IR (N = 29) IR (N = 11) St. “t P
Mean ± SD Range Mean ± SD Range
Age (years) 10.8 2.44 8-16 12.5 3.09 8-16 1.82 0.076
BMI (kg/m2) 19.6 4.69 13.6-30.6 21.4 7.25 16.3-40.4 0.94 0.35 (NS)
Liver span 8.75 3.98 5-19 10.00 4.07 5-15 0.76 0.44 (NS)
Spleen size 3.32 2.38 0-7 4.30 3.78 0-10 0.68 0.49 (NS)
Duration of bl transfusion (years) 9.38 2.50 6-15 12.55 2.75 7.9-15.6 3.47 =0.001 (HS)
Hb% 8.43 1.18 6.3-10.0 8.62 1.11 6.5-10.0 0.45 0.65 (NS)
ALT(U/L) 52.0 13.5 35-93 64.7 17.1 37.5-96 2.46 0.018 (S)
AST(U/L) 49.7 8.54 35-65 57.4 18.47 36.2-95 1.83 0.075
Serum ferritin (ng/ml) 2447.2 1044.4 1103-5426 3759.7 1617.7 1234-6989 2.63 0.008 (S)
Fasting plasma glucose 98.4 18.94 70-125 121.5 17.40 88-151 3.17 0.002 (S)
2 h pp plasma glucose 146.4 26.8 99-199 184.7 29.3 144-225 3.02 0.003 (S)
Fasting plasma insulin 7.06 3.69 2.62-20.66 21.34 25.64 3.34-74.9 2.67 0.008 (S)
  1. St. “t” Student t test, IR insulin resistance, ALT alanine aminotransferase, AST aspartate aminotransferase