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Table 1 Comparison between patient and control groups

From: Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major

Variable Patients (N = 40) Controls (N = 30) St. “t” P
Mean ± SD Range Mean ± SD Range
Age (years) 11.0 2.86 8-16 10.8 2.49 8-16 0.31 0.75
Sex (no., %) Male 27 (67.5%) 18 (60%) χ2 (0.42) 0.51
Female 13 (32.5%) 12 (40%)
BMI (kg/m2) 20.1 5.47 13.6-40.4 19.6 2.98 15.4-24.8 0.43 0.66 (NS)
Hb% 8.49 1.15 6.3-10.0 10.68 1.34 8.4-13.0 7.34 < 0.001 (HS)
ALT (U/L) 55.5 15.4 35-96 48.3 4.22 41-59 2.47 0.016 (S)
AST (U/L) 51.8 12.3 35-95 43.9 5.0 34-53 3.31 0.002 (S)
S ferritin (ng/ml) 2808.1 1344.0 1103-6989 20 3.0 30-18 4.05 < 0.001 (HS)
Fasting plasma glucose (mg/dl) 104.7 21.0 70-151 90.4 11.9 74-108 3.1 0.002 (S)
Fasting plasma insulin (μU/ml) 10.9 14.8 2.62-74.9 8.0 7.1 2.98-43.7 0.99 0.32
2 h pp plasma glucose (mg/dl) 157.0 32.2 99-225 114.5 10.5 95-130 St. “t” = 6.94 < 0.001 (HS)
HOMA-IR% 3.21 4.77 0.66-27.9 1.51 0.49 0.55-2.39 2.43 0.015 (S)
IR (no., %) No 29 (72.5%) 30 (100%)   0.002 (S)
Yes 11 (27.5%) 0 (0%)  
  1. St. “t” Student “t” test, S Significant, HS highly significant, ALT alanine aminotransferase, AST aspartate aminotransferase, HOMA-IR Homeostasis Model Assessment of insulin resistance index, IR insulin resistance