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Table 1 Comparison between patient and control groups

From: Evaluation of glycemic abnormalities in children and adolescents with β-thalassemia major

Variable

Patients (N = 40)

Controls (N = 30)

St. “t”

P

Mean

± SD

Range

Mean

± SD

Range

Age (years)

11.0

2.86

8-16

10.8

2.49

8-16

0.31

0.75

Sex (no., %)

Male

27 (67.5%)

18 (60%)

χ2 (0.42)

0.51

Female

13 (32.5%)

12 (40%)

BMI (kg/m2)

20.1

5.47

13.6-40.4

19.6

2.98

15.4-24.8

0.43

0.66 (NS)

Hb%

8.49

1.15

6.3-10.0

10.68

1.34

8.4-13.0

7.34

< 0.001 (HS)

ALT (U/L)

55.5

15.4

35-96

48.3

4.22

41-59

2.47

0.016 (S)

AST (U/L)

51.8

12.3

35-95

43.9

5.0

34-53

3.31

0.002 (S)

S ferritin (ng/ml)

2808.1

1344.0

1103-6989

20

3.0

30-18

4.05

< 0.001 (HS)

Fasting plasma glucose (mg/dl)

104.7

21.0

70-151

90.4

11.9

74-108

3.1

0.002 (S)

Fasting plasma insulin (μU/ml)

10.9

14.8

2.62-74.9

8.0

7.1

2.98-43.7

0.99

0.32

2 h pp plasma glucose (mg/dl)

157.0

32.2

99-225

114.5

10.5

95-130

St. “t” = 6.94

< 0.001 (HS)

HOMA-IR%

3.21

4.77

0.66-27.9

1.51

0.49

0.55-2.39

2.43

0.015 (S)

IR (no., %)

No

29 (72.5%)

30 (100%)

 

0.002 (S)

Yes

11 (27.5%)

0 (0%)

 
  1. St. “t” Student “t” test, S Significant, HS highly significant, ALT alanine aminotransferase, AST aspartate aminotransferase, HOMA-IR Homeostasis Model Assessment of insulin resistance index, IR insulin resistance