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Table 1 Summary of the studies selected for this systematic review

From: Effectiveness of two concentrations 12% versus 38% of silver diamine fluoride in arresting cavitated dentin caries among children: a systematic review

Study ID Subjects age (years)
Range, mean (SD)
Teeth Total no. of patients/drop out Grouping Trial length/months Outcome
Yee et al. [16] 3–9, 5.2 (1.2) Primary teeth 976 children
At 6 months, 908
At 12 months, 768
At 24 months, 634
Group 1: One application of 38% SDF for 2 min without a reducing agent
Group 2: One application of 38% SDF for 2 min with tea as a reducing agent
Group 3: One application of 12% SDF for 2 min without a reducing agent
Group 4: No treatment for carious teeth
This was the control group.
24 Mean number of active cavitated surfaces at baseline that changed at 6, 12, and 24 months’ follow-up examination into surfaces with arrested cavitated caries
Fung et al. [17, 18]* 3–4, 3.8 (0.6) Primary teeth 888 children
At 6 months, 888
At 12 months, 850
At 18 months, 831
at 24 months, 806
at 30 months, 799
Group 1: 12% SDF applied every 12 months
Group 2: 12% SDF applied every 6 months
Group 3: 38% SDF applied every 12 months
Group 4: 38% SDF applied every 6 months
18 (2016)
30 (2018)
Tooth surface-level caries arrest rates at 6, 12, 18, 24, and 30 months’ examinations n/N (%).
Mean (SD) numbers of tooth surfaces with arrested caries at 30 months follow-up.
  1. *Fung et al.: Two publication reports with different follow-up [first 2016 (6, 12, and 18 months follow-up); second 2018 (24 and 30 months follow-up)]